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NARA Subscribed1
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Springer Nature1
Journal
Journal of Molecular Medicine1
Publication Year
20221
Lisa Pechtold results 1 · Newest (Page 1/1, per page 25)
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Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B2 receptor antagonismNARA Subscribed
Journal of Molecular Medicine · 2022 · Vol. 100 · Issue 4 · Springer
Constanze A. Jakwerth; Martin Feuerherd; Ferdinand M. Guerth; Madlen Oelsner; Linda Schellhammer; Johanna Giglberger; Lisa Pechtold; Claudia Jerin; Luisa Kugler; Carolin Mogler; Bernhard Haller; Anna Erb; Barbara Wollenberg; Christoph D. Spinner; Thorsten Buch; Ulrike Protzer; Carsten B. Schmidt-Weber; Ulrich M. Zissler; Adam M. Chaker
SARS-CoV-2 has evolved to enter the host via the ACE2 receptor which is part of the kinin-kallikrein pathway. This complex pathway is only poorly understood in context of immune regulation but critical to control infection. This study examines SARS-CoV-2-infection and epithelial mechanisms of the kinin-kallikrein-system at the kinin B 2 receptor level in SARS-CoV-2-infection that is of direct translational relevance. From acut...
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