Ludovic Pascal results 17
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Ocean deoxygenation caused non‐linear responses in the structure and functioning of benthic ecosystemsNARA Subscribed
The O 2 content of the global ocean has been declining progressively over the past decades, mainly because of human activities and global warming. Nevertheless, how long‐term deoxygenation affects macrobenthic communities, sediment biogeochemistry and their mutual feedback remains poorly understood. Here, we evaluate the response of the benthic assemblages and biogeochemical functioning to decreasing O 2 concentrations along t...
From organismal physiology to ecological processes: Effects of nutrient enrichment and salinity variation in a freshwater ecosystemNARA Subscribed
Environmental stressors have profound implications for species, communities, and ecosystems by altering fundamental processes. With increasing human impacts on aquatic ecosystems, two main scenarios have been reported: (1) the spatiotemporal superposition of multiple stressors, leading to interactions among them and (2) intensifying environmental gradients, leading to threshold responses. However, studies designed to assess th...
Growing genetically resistant plants allows pathogen populations to be controlled and reduces the use of pesticides. However, pathogens can quickly overcome such resistance. In this context, how can we achieve sustainable crop protection? This crucial question has remained largely unanswered despite decades of intense debate and research effort. In this study, we used a bibliographic analysis to show that the research field of...
Tipping points and multiple drivers in changing aquatic ecosystems: A review of experimental studiesNARA Subscribed
Natural ecosystems are experiencing unprecedented rates of change due to anthropogenic activities and global change, leading to either gradual changes in a given response or tipping points. While the tipping point concept has been tested in an array of habitats since the 1960s, the spatiotemporal superposition of multiple drivers in different ecosystems needs to be considered when investigating the response of species, communi...
Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid AssembliesNARA Subscribed
The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer’s disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant Aβ have shown that hexameric Aβ in particular acts as a critical nucleus for Aβ self-assembly. We recently isolated hexameric Aβ assemblies from a cellular model,...
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