Background Cetuximab is extensively used in the treatment of metastatic colorectal cancer (mCRC). However, resistance poses a significant challenge to successful therapy. Recently, paraptosis, a non-classical programmed cell death, has garnered increased attention for its potential application value in antitumor treatments. We aimed to identify the essential pathways and signaling molecules involved in paraptosis inhibition an...

The intensive generation of industrial solid waste (ISW) in industrial parks poses a severe threat to the water and soil environment. To address the lack of system‐level guidance strategies for ISW management (ISWM), the paper proposes a systematic ISWM framework within the context of the circular economy principle and applies it to a prominent eco‐industrial park in China. This framework is founded on the metabolic characteri...