Phytoplankton blooms structure primary production and food‐web dynamics in the Gulf of Alaska, yet their response to recent warming and marine heatwaves (MHWs) remains poorly described. Using a parametric Gaussian framework applied to 21 years of satellite chlorophyll a (Chl a ), this study classified daily Chl a timeseries into double‐bloom, single spring‐bloom, single fall‐bloom, and no‐bloom regimes and related these to lar...

Potato dormancy is a major obstacle in post-harvest evaluations for the certification of seed. Objectives of this study were to evaluate the efficacy of several treatments to break dormancy and induce sprouting soon after harvest for Russet Burbank, Clearwater Russet, and Umatilla Russet. Treatments included: (a) control held at 18.3 C, (b) cold-stratification held at 4.4 C for two weeks, (c) temperature fluctuation held at 4....

Handling potatoes at harvest and throughout transloading operations can result in two main impact injuries: blackspot and shatter bruises. The objective of this study was to examine the development of blackspot and shatter bruises over a 24 to 48-h period as influenced by cultivar, impact height and holding temperature with the intent to identify whether more rapid, on-farm bruise evaluations could be used to facilitate change...

Potato virus Y (PVY) is an important pathogen in seed potato production that may cause seed lots to be downgraded or rejected for certification. A study was conducted to determine if mother seed tuber size influences the prevalence of PVY within a seed sample during evaluations of seed-borne infection in a grow-out. The trial was conducted using Russet Norkotah (two growing seasons) and Umatilla Russet (one growing season). Se...

Rationale There is increasing interest in establishing psychedelic research programs at academic medical centers. However, psychedelics are intensely psychoactive, carry considerable sociopolitical baggage, and most are Schedule I drugs, creating significant potential impediments to implementation. There is little formal guidance for investigators on navigating the complex on-the-ground obstacles associated with establishing p...

Handling potatoes individually or collectively in packages can create opportunities for potatoes to develop quality defects including blackspot and shatter bruise. Three trials were conducted to examine how handling packaged potatoes can influence the risk for physical damage including shatter and blackspot bruise. An impact recording device was used to record peak acceleration (max g-force) in common fresh market packaging op...

RO7297089, an anti-B-cell maturation antigen (BCMA)/CD16A bispecific tetravalent antibody, is being developed as a multiple myeloma (MM) therapeutic. This study characterized nonclinical pharmacokinetics (PK), pharmacodynamics (PD), soluble BCMA (sBCMA), and soluble CD16 (sCD16) changes following administration of RO7297089 to support clinical trials. Unbound and total RO7297089 concentrations were measured in cynomolgus monke...

Identifying the genetic architecture of complex phenotypes is a central goal of modern biology, particularly for disease‐related traits. Genome‐wide association methods are a classical approach for identifying the genomic basis of variation in disease phenotypes, but such analyses are particularly challenging in natural populations due to sample size difficulties. Extensive mark–recapture data, strong linkage disequilibrium an...

Microgeographic adaptation provides a particularly interesting context for understanding the genetic basis of phenotypic divergence and may also present unique empirical challenges. In particular, plant adaptation to extreme soil mosaics may generate barriers to gene flow or shifts in mating system that confound simple genomic scans for adaptive loci. Here, we combine three approaches – quantitative trait locus (QTL) mapping o...

We assembled data from a global network of automated lake observatories to test hypotheses regarding the drivers of ecosystem metabolism. We estimated daily rates of respiration and gross primary production (GPP) for up to a full year in each lake, via maximum likelihood fits of a free‐water metabolism model to continuous high‐frequency measurements of dissolved oxygen concentrations. Uncertainties were determined by a bootstr...