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The AAPS Journal · 2025 · Vol. 27 · Issue 6 · Springer
Antibody–drug conjugates (ADCs) represent a rapidly expanding class of therapeutics, uniquely combining the specificity of monoclonal antibodies with the potency of cytotoxic small-molecule payloads. Due to their inherent structural complexity and heterogeneous composition, accurate characterization and quantification of ADCs pose significant bioanalytical challenges. This review discusses recent advancements in bioanalytical...
Journal of Fish Biology · 2024 · Vol. 104 · Issue 3 · Wiley
Scomberomorus guttatus has been subjected to a series of synonym assignations over the years. Its taxonomy has been mired with ambiguities due to the greater‐than‐average morphological variations observed in samples from different regions. An integrated taxonomic revision with molecular support indicated that the species that was thought to be a single entity, in reality, is a complex of three distinct species. They are morpho...
Frontiers in Marine Science · 2022 · Vol. 9 · Frontiers
The genus Scomberomorus , with 18 nominal species, sustains a significant heterogeneous fishery throughout its range. The sole molecular systematic study of this genus concerned the species group S. regalis , which contains the new world taxa. The species diversity of Scomberomorus in the northern Indian Ocean has not been studied at the molecular level, often leading to misidentifications. Here, novel genetic data are provide...
Human Genetics · 2020 · Vol. 139 · Issue 2 · Springer
Orofacial clefts (OFCs) are among the most prevalent craniofacial birth defects worldwide and create a significant public health burden. The majority of OFCs are non-syndromic, and the genetic etiology of non-syndromic OFCs is only partially determined. Here, we analyze whole genome sequence (WGS) data for association with risk of OFCs in European and Colombian families selected from a multicenter family-based OFC study. This...