Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study aimed to develop gastro-retentive floating tablets of famotidine using hot-melt extrusion (HME) and fused deposition modeling (FDM) 3D printing approach to enhance its solubility, prolong gastric residence, and achieve extended drug release. Famotidine was incorporated into various polymer...

Purpose The purpose of this research was to develop and characterize dual-drug Isoniazid-Pyridoxine gummies using Semisolid Extrusion (SSE) 3D printing technology, aimed at personalized dosing for a broad patient demographic, from pediatric to geriatric. This study leverages SSE 3D printing, an innovative approach in personalized medicine, to enable precise dose customization and improve patient adherence. By formulating dual...

Although N 2 ‐fixing cyanobacteria contribute significantly to oceanic sequestration of atmospheric CO 2 , little is known about how N 2 fixation and carbon fixation (primary production) interact in natural populations of marine cyanobacteria. In a developing cyanobacterial bloom in the Baltic Sea, rates of N 2 fixation (acetylene reduction) showed both diurnal and longer‐term fluctuations. The latter reflected fluctuations in...