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A human PBMC-based new approach method reveals PFAS-driven T-cell proliferation and immune dysregulationNARA Subscribed
Immunotoxicity has emerged as a key health concern for per- and polyfluoroalkyl substances (PFAS), with animal studies showing reduced T-dependent antibody responses (TDAR) and epidemiological studies reporting decreased vaccine antibody titres. Notably, immunotoxicity is considered one of the most sensitive endpoints for PFAS exposure and has been used to inform regulatory guidance and health-based values. Given that more tha...
First genetic confirmation of the smooth hammerhead shark ( Sphyrna zygaena , Linnaeus, 1758) in French Polynesian watersNARA Subscribed
The smooth hammerhead shark ( Sphyrna zygaena ) has never been formally confirmed in French Polynesian waters. Observations of solitary hammerhead sharks suggested the presence of an unrecorded species. Two specimens captured off Tahiti were morphologically and genetically examined. Both matched traits of the smooth hammerhead and COI barcoding confirmed >99% similarity to reference sequences in the NCBI and BOLD databases. Th...