In the absence of horizontal migration, salt marshes must build vertical elevation to persist under sea level rise by building soil through primary production and inorganic sediment deposition. Here we examine a phenomenon observed in a high salinity salt marsh estuary whereby leaf-surface coatings form on Spartina alterniflora (aka Sporobolus alterniflorus ) leaves and we investigate whether these coatings can inhibit photosy...

Gravitational volcanic flank collapses are recurrent processes producing large-scale landslides, commonly associated with secondary instabilities and destructive tsunamis. Ocean island volcanoes are particularly prone to such failures, yet the dynamics, emplacement mechanisms, and tsunamigenic potential of gravitational collapses remain poorly constrained due to the scarcity of direct observations. The ~ 68 ka Monte Amarelo fl...

Although plasma pTau181 has been shown to accurately discriminate patients with Alzheimer’s disease from healthy older adults, there are few studies of plasma biomarkers among middle-aged populations. Given the potential utility of plasma AD biomarkers such as pTau181 in screening for disease risk, examining pTau181 in a middle-aged cohort without AD is important for future implementation. The objectives of this study were to...

Climate change threatens biodiversity when species cannot tolerate, adapt to, or track shifting environmental conditions to stay within their climatic niches. A major unresolved question is whether and how species' genetic diversity modulates these dynamics, buffering against range contractions or facilitating range expansions. To test this, we integrated the largest global databases of species range shifts and genetic diversi...

Tyrosine kinase inhibitors (TKIs) are widely used in cancer therapy yet are strongly associated with acute and chronic cardiotoxicity in patients. There is a critical need to advance our understanding of the pathophysiology that underlies TKI-mediated cardiotoxicity, and central to this is the use of reproducible and relevant preclinical models, which are employed in the evaluation of TKIs across the drug discovery pipeline. W...