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NARA Subscribed1
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Springer Nature1
Journal
Angiogenesis1
Publication Year
20211
M. Beter results 1 · Newest (Page 1/1, per page 25)
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Author: M. Beter ×Clear All Filters
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BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGFNARA Subscribed
Angiogenesis · 2021 · Vol. 24 · Issue 1 · Springer
H. H. Pulkkinen; M. Kiema; J. P. Lappalainen; A. Toropainen; M. Beter; A. Tirronen; L. Holappa; H. Niskanen; M. U. Kaikkonen; S. Ylä-Herttuala; Johanna P. Laakkonen
The BMP/TGFβ-Smad, Notch and VEGF signaling guides formation of endothelial tip and stalk cells. However, the crosstalk of bone morphogenetic proteins (BMPs) and vascular endothelial growth factor receptor 2 (VEGFR2) signaling has remained largely unknown. We demonstrate that BMP family members regulate VEGFR2 and Notch signaling, and act via TAZ-Hippo signaling pathway. BMPs were found to be regulated after VEGF gene transfer...
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