M. Bloom results 55
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Expression of Enterocin A in Saccharomyces cerevisiaeNARA Subscribed
Recombinant expression in the yeast Saccharomyces cerevisiae offers an alternative approach to developing large-scale production systems for class II bacteriocins from lactic acid bacteria, such as enterocin A, mundticin ST4SA and plantaricin 423. An important consideration for bacteriocin activity is disulphide bond formation: mature mundticin ST4SA has one, and plantaricin 423 and enterocin A each have two disulphide bonds....
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Congo Basin Carbon Cycle Responses to Global ChangeNARA Subscribed
The Congo Basin and its contiguous forests harbor globally significant carbon stocks, estimated at 65 gigatons of C (GtC) above and belowground. Despite rising temperatures and intensifying droughts, they have remained a carbon sink, albeit weak: 0.26–0.50 GtC yr. −1 carbon uptake since 1980. However, these forests' carbon stocks and fluxes, including gross primary productivity, respiration, net primary productivity, and river...
Combining Observations and Models: A Review of the CARDAMOM Framework for Data‐Constrained Terrestrial Ecosystem ModelingNARA Subscribed
The rapid increase in the volume and variety of terrestrial biosphere observations (i.e., remote sensing data and in situ measurements) offers a unique opportunity to derive ecological insights, refine process‐based models, and improve forecasting for decision support. However, despite their potential, ecological observations have primarily been used to benchmark process‐based models, as many past and current models lack the c...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
Defining an ageing-related pathology, disease or syndrome: International Consensus StatementNARA Subscribed
Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased health span. With advancing age, the increased prevalence of ageing-related diseases can have a significant impact on health status, functional capacity and quality of life. It is therefore vital to develop comprehensive classification and staging systems for ageing-related pathologies, diseases and syndrom...
Heterologous Expression of Plantaricin 423 and Mundticin ST4SA in Saccharomyces cerevisiaeNARA Subscribed
Antimicrobial peptides or bacteriocins are excellent candidates for alternative antimicrobials, but high manufacturing costs limit their applications. Recombinant gene expression offers the potential to produce these peptides more cost-effectively at a larger scale. Saccharomyces cerevisiae is a popular host for recombinant protein production, but with limited success reported on antimicrobial peptides. Individual recombinant...
Forest productivity recovery or collapse? Model‐data integration insights on drought‐induced tipping pointsNARA Subscribed
More frequent and severe droughts are driving increased forest mortality around the globe. We urgently need to describe and predict how drought affects forest carbon cycling and identify thresholds of environmental stress that trigger ecosystem collapse. Quantifying the effects of drought at an ecosystem level is complex because dynamic climate–plant relationships can cause rapid and/or prolonged shifts in carbon balance. We e...
The ocean continues to be a sink for microparticle (MP) pollution, which includes microplastics and other anthropogenic debris. While documentation of MP in marine systems is now common, we lack information on rates of MP ingestion by baleen whales and their prey. We collected and assessed MP loads in zooplankton prey and fecal samples of gray whales ( Eschrichtius robustus ) feeding in coastal Oregon, USA and produced the fir...
Many challenges remain before we can fully understand the multifaceted role that natural organic matter (NOM) plays in soil and aquatic systems. These challenges remain despite the considerable progress that has been made in understanding NOM’s properties and reactivity using the latest analytical techniques. For nearly 4 decades, the International Humic Substances Society (IHSS, which is a non-profit scientific society) has d...
Purposely introduced in 1879, Pacific coast Striped Bass Morone saxatilis once supported a commercial fishery and currently supports a recreational fishery in the San Francisco Estuary Watershed, CA, USA; however, the population has been in decline for decades. Since little is known about sub-adult behavior on the Pacific coast, we used acoustic telemetry to investigate seasonal movement patterns and habitat use across three r...
Time for speciation and niche conservatism explain the latitudinal diversity gradient in clupeiform fishesNARA Subscribed
Aim The latitudinal diversity gradient of increasing species richness from poles to equator is one of the most striking and pervasive spatial patterns of biodiversity. Climate appears to have been key to the formation of the latitudinal diversity gradient, but the processes through which climate shaped species richness remain unclear. We tested predictions of the time for speciation, carrying capacity and diversification rate...
Water balance affects foliar and soil nutrients differentlyNARA Subscribed
Seventy five percent of the world's food crops benefit from insect pollination. Hence, there has been increased interest in how global change drivers impact this critical ecosystem service. Because standardized data on crop pollination are rarely available, we are limited in our capacity to understand the variation in pollination benefits to crop yield, as well as to anticipate changes in this service, develop predictions, and...