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Loss and Transformation of Coastal Wetlands due to Global Change in the Conterminous United States: Past, Present, and FutureNARA Subscribed
Coastal wetlands are being transformed by global change, impacting the ecological and societal benefits provided by these ecosystems. Synthesizing knowledge of historical and expected future transformations in coastal wetlands can help inform forward-looking planning and stewardship efforts. Here, we review anticipated future ecological transformations in coastal wetlands of the conterminous United States and contrast them wit...
Urbanization drives genetic erosion and population structure in a historically connected carnivore populationNARA Subscribed
Urbanization is a dominant driver of habitat fragmentation globally, creating small, isolated wildlife populations vulnerable to accelerated genetic drift, reduced genetic diversity, and increased population differentiation. We investigated how urban development affects the genetic structure of caracals ( Caracal caracal ) in Cape Town, South Africa using microsatellites and mitochondrial DNA sequence data. Sampling across fou...
Long‐Term Ecological Baselines and Critical Thresholds in Ombrotrophic Peatlands of Europe: Implications for Restoration StrategiesNARA Subscribed
Maintaining appropriate peatland hydrology, notably through the regulation of the depth to water table (DWT), is crucial for peatland conservation, restoration, and the mitigation of greenhouse gas (GHG) emissions. We assess the long‐term ecological impact of hydrological changes, primarily induced by drainage, in ombrotrophic peatlands across Europe. Our analysis is based on novel palaeoecological data from seven peat cores c...
Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs) have shown considerable promise as restorative stroke treatment. In a head-to-head comparison in mice exposed to transient proximal middle cerebral artery occlusion (MCAO), sEVs obtained from MSCs cultured under hypoxic conditions particularly potently enhanced long-term brain tissue survival, microvascular integrity, and angiogenesis. These obs...
The highs and lows of monoamine oxidase as molecular target in cancer: an updated reviewNARA Subscribed
The global burden of cancer as a major cause of death and invalidity has been constantly increasing in the past decades. Monoamine oxidases (MAO) with two isoforms, MAO-A and MAO-B, are mammalian mitochondrial enzymes responsible for the oxidative deamination of neurotransmitters and amines in the central nervous system and peripheral tissues with the constant generation of hydrogen peroxide as the main deleterious ancillary p...
Obesity, diabetes, and their cardiovascular and hepatic comorbidities are alarming public health issues of the twenty-first century, which share mitochondrial dysfunction, oxidative stress, and chronic inflammation as common pathophysiological mechanisms. An increasing body of evidence links the combined exposure to multiple environmental toxicants with the occurrence and severity of metabolic diseases. Endocrine disruptors (E...
A Functional Response in Resource Selection Links Multiscale Responses of a Large Carnivore to Human Mortality RiskNARA Subscribed
Theory suggests that animals make hierarchical, multiscale resource selection decisions to address the hierarchy of factors limiting their fitness. Ecologists have developed tools to link population‐level resource selection across scales; yet, theoretical expectations about the relationship between coarse‐ and fine‐scale selection decisions at the individual level remain elusive despite their importance to fitness. With GPS‐te...
Combining storm flood water level and topography to prioritize inter-basin transfer of non-native aquatic species in the United StatesNARA Subscribed
Flooded areas can create temporary connections between adjacent drainages and are a relatively understudied pathway for the spread of aquatic invasive species. The Nonindigenous Aquatic Species Database’s Flood and Storm Tracker maps were developed to help natural resource managers with post-storm aquatic invasive species detection and assessment efforts. As of the summer of 2023, 16 Flood and Storm Tracker maps have been publ...
Dominance and rarity in tree communities across the globe: Patterns, predictors and threatsNARA Subscribed
Aim Ecological and anthropogenic factors shift the abundances of dominant and rare tree species within local forest communities, thus affecting species composition and ecosystem functioning. To inform forest and conservation management it is important to understand the drivers of dominance and rarity in local tree communities. We answer the following research questions: (1) What are the patterns of dominance and rarity in tree...