PJVK gene was recently shown to create hypervulnerability to sound in humans and was the first human gene implicated in non-syndromic hearing impairment due to neural defect. Targeted next-generation sequencing of over 150 known deafness genes was performed in the proband. Sanger sequencing was used to validate the PJVK variant and confirm familial segregation of the disease. A minigene-based assay has been performed to assess...

Aim To identify the broad‐scale oceanic migration routes (‘marine flyways’) used by multiple pelagic, long‐distance migratory seabirds based on a global compilation of tracking data. Location Global. Time Period 1989–2023. Major Taxa Studied Seabirds (Families: Phaethontidae, Hydrobatidae, Diomedeidae, Procellariidae, Laridae and Stercorariidae). Methods We collated a comprehensive global tracking dataset that included the mig...

Biological dinitrogen (N 2 ) fixation, the energetically expensive conversion of N 2 gas to ammonia, plays an essential role in balancing the nitrogen budget in the ocean. Accumulating studies show detectable N 2 fixation rates below the euphotic zone in various marine systems, revealing new insights of marine N 2 fixation. However, the reported rates are highly variable and frequently fall close to detection limits, raising t...

Six gridded temperature datasets (T‐datasets) were evaluated for the first time over the South American continent, through the case study of Bolivia, by comparing them with temperature records acquired from 82 meteorological stations spanning the 1995–2010 period. The comparisons were carried out at the daily time step considering different seasons (annual scale, austral summer and austral winter) and regions (Amazon, La Plata...

The record of open‐air Middle Palaeolithic sites in the Iberian Peninsula—specifically in the Mediterranean basin—is scarce, hampering the interpretation of the landscape use strategies developed by Neanderthals in this area. In this work, we present Los Aljezares, a new Middle Palaeolithic site found in Pleistocene fluvio‐lacustrine deposits in the sedimentary basin of the Vinalopó River. A U/Th age (132 ± 10 ka) from associa...

The oceanic dissolved organic phosphorus (DOP) pool is mainly composed of P-esters and, to a lesser extent, equally abundant phosphonate and P-anhydride molecules. In phosphate-limited ocean regions, diazotrophs are thought to rely on DOP compounds as an alternative source of phosphorus (P). While both P-esters and phosphonates effectively promote dinitrogen (N 2 ) fixation, the role of P-anhydrides for diazotrophs is unknown....

Complex epigenetic changes occur during plant reproduction. These regulations ensure the proper transmission of epigenetic information as well as allowing for zygotic totipotency. In Arabidopsis , the main DNA methyltransferase is called MET1 and is responsible for methylating cytosine in the CG context. The Arabidopsis genome encodes for three additional reproduction-specific homologs of MET1 , namely MET2a , MET2b and MET3....

Every year, billions of birds undertake extensive migrations between breeding and non-breeding areas, facing challenges that require behavioural adjustments, particularly to flight timing and duration. Such adjustments in daily activity patterns and the influence of extrinsic factors (e.g., environmental conditions, moonlight) have received much more research attention in terrestrial than marine migrants. Taking advantage of t...

This study compared standard of care testing (SOC) to BioFire® FilmArray® Pneumonia plus Panel (PN plus ). PN plus detects 15 bacteria with semiquantitative log bin values, 7 antibiotic resistance markers, three atypical bacteria (AB), and eight viral classes directly from bronchoalveolar lavage-like specimens (BLS) and sputum-like specimens (SLS). Fifty-two laboratories from 13 European countries and Israel tested 1234 BLS an...

The current lack of knowledge on the trophic ecology of scyphozoans, particularly at the benthic stage, prevents a full understanding of the controls on many jellyfish blooms. The blooming scyphozoan ( Aurelia coerulea ) completes its entire life cycle in the Thau lagoon (southern France), where the annual population dynamics of both its benthic and pelagic stages have been described. This offered an exceptional framework to i...