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Development of a question prompt list to support Consent for Genomic Testing (CoGenT) and researchNARA Subscribed
While genomic testing is increasingly utilised to personalise cancer treatment, its complexity creates challenges in achieving informed consent. Partnering with patients, carers, researchers and health professionals, we developed a Question Prompt List (QPL) aiming to support communication and informed consent for tumour profiling and genomic research in oncology. Participants ( n = 38) included cancer patients participating (...
Summary Ruminococcus champanellensis is a keystone species in the human gut that produces an intricate cellulosome system of various architectures. A variety of cellulosomal enzymes have been identified, which exhibit a range of hydrolytic activities on lignocellulosic substrates. We describe herein a unique R. champanellensis scaffoldin, ScaK, which is expressed during growth on cellobiose and comprises a cohesin module and a...
A Jaundice Syndrome occurs sporadically among sea‐pen‐farmed Chinook Salmon in British Columbia, the westernmost province of Canada. Affected salmon are easily identified by a distinctive yellow discolouration of the abdominal and periorbital regions. Through traditional diagnostics, no bacterial or viral agents were cultured from tissues of jaundiced Chinook Salmon; however, piscine reovirus (PRV) was identified via RT‐ rPCR...
Individual personalities predict social behaviour in wild networks of great tits ( Parus major)NARA Subscribed
Social environments have an important effect on a range of ecological processes, and form a crucial component of selection. However, little is known of the link between personality, social behaviour and population structure. We combine a well‐understood personality trait with large‐scale social networks in wild songbirds, and show that personality underpins multiple aspects of social organisation. First, we demonstrate a relat...
Exclusion probabilities for single‐locus paternity analysis when related males compete for matingsNARA Subscribed
The statistical power of single‐locus paternity analyses has previously been assessed by calculating an expected exclusion probability ( E ), the probability of excluding a randomly chosen nonfather. This E ‐statistic assumes that putative sires are a random selection of individuals from a panmictic study population. In species that display male natal philopatry, closely related individuals may be the principal competitors for...
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