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Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Relative homogenization methods assume that measurements of nearby stations experience similar climate signals and rely therefore on dense station networks with high‐temporal correlations. In developing countries such as Peru, however, networks often suffer from low‐station density. The aim of this study is to quantify the influence of network density on homogenization. To this end, the homogenization method HOMER was applied...
Climate indices facilitate the interpretation of expected climate change impacts for many sectors in society, economy, and ecology. The new localized data set of climatic change signals for temperature and precipitation presented by Zubler et al. (Clim Change, 2013) is applied for an analysis of frequently used climate indices in Switzerland. The indices considered are: number of summer days and tropical nights, growing season...
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