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Relationship of temperature with declines and persistence of Myotis lucifugus after white‐nose syndromeNARA Subscribed
White‐nose syndrome (WNS), caused by the fungus Pseudogymnoascus destructans (Pd), ranks among the most devastating wildlife diseases in recent history and is driving severe declines in North American bats. Identifying environmental factors that influence both the severity of population crashes and the potential for population persistence is essential for effective mitigation. We used a long‐term dataset from hibernacula acros...
Lynch syndrome caused by a pathogenic SINE-VNTR-Alu (SVA) insertion in MSH2 gene identified by long-read DNA sequencingNARA Subscribed
Lynch syndrome, the most common hereditary cancer syndrome, is caused by germline pathogenic variants in DNA mismatch repair (MMR) genes. Identifying complex or structural MMR gene pathogenic variants can be challenging with short-read sequencing resulting in patients with unexplained MMR-deficient tumours. In this study, we report multiple members of a family who developed MSH2-deficient tumours where clinical multi-gene pane...
Local Angler Knowledge Reveals Declines in Fishing Quality for Black Bass in Lakes of Eastern OntarioNARA Subscribed
Local ecological knowledge can be useful to assess data‐limited fisheries such as the Ontario Black Bass ( Micropterus spp.) recreational fishery. We surveyed local anglers using the Life History Calendar approach to determine if there were perceived changes in fishing quality for Black Bass in eastern Ontario across different time periods. For both species (Largemouth Bass and Smallmouth Bass), respondents noted declines in n...
In a rapidly warming Arctic, genetic variation might serve to buffer organisms against the effects of environmental change, such as sea ice loss and ocean warming. Yet, this concept remains largely unexplored because comprehensive genome‐wide studies across the full ranges of Arctic marine taxa are rare. Bowhead whales ( Balaena mysticetus ) have a strong association with sea ice and polar water masses, a long history of human...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Shortleaf Pine (Pinus echinata): Management Challenges, Knowledge Gaps, and Opportunities for an Unsung SpeciesNARA Subscribed
Shortleaf pine has the broadest range of the southern pine species, occurring in 22 states and extending north into New Jersey, Pennsylvania, and New York (Staten Island). Shortleaf pine has been understudied compared to loblolly pine and longleaf pine, typically favored for timber production and conservation value, respectively. The extensive range of shortleaf pine contributes to a high degree of variability within and among...