M. Esteban results 327
· Newest (Page 1/14, per page 25)
Author: M. Esteban ×Clear All Filters
Search Results
Intraspecific Variation of Edwardsiella anguillarum From Non‐Anguillid Fish From Varied Geographic OriginsNARA Subscribed
Edwardsiella anguillarum is a gram‐negative bacterium, synonymous with previously described atypical, fish‐pathogenic Edwardsiella tarda . Originally described from eels in 2015, E. anguillarum is an important global fish pathogen, particularly in tilapia. This study describes intraspecific phenotypic and genotypic variability among 17 E. anguillarum isolates from non‐anguillid fish hosts and varied geographic origins. Isolate...
Soil Microbial Diversity and Network Organization Respond to Land Use and Agricultural Inputs WorldwideNARA Subscribed
Soil microbiomes are critical for ecosystem functioning, yet the global influences of climate and agricultural practices on their diversity and structure remain incompletely characterized. Here we analyzed 1921 soil samples from 33 countries worldwide across diverse biomes to assess how climate gradients and agricultural inputs, including pesticides and fertilizers, shape prokaryotic and fungal communities. We found that micro...
Tilapia Lake Virus (TiLV) is a significant threat to global tilapia aquaculture, highlighting the need for rapid and accurate diagnostic methods to manage outbreaks and minimise economic losses. This study presents the development and partial validation of a one‐pot assay integrating RT‐LAMP with the CRISPR/Cas12b system for sensitive and specific TiLV detection. This assay amplifies viral RNA using RT‐LAMP, while CRISPR/Cas12...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Identification of Genetic Variation Associated With Heat Tolerance in Cowpea ( Vigna unguiculata L. Walp.)NARA Subscribed
Heat tolerance is an important trait in cowpea, a crop that is the primary protein source for a large portion of the human population in sub‐Saharan Africa. Cultivated, landrace, semi‐wild, and wild cowpea grow across the region in diverse climatic conditions. This study used environmental association (envGWAS) and allele‐frequency outlier approaches across a panel of 580 gene bank accessions to identify genomic regions associ...
Deep rock salt formations can be drilled and solution-mined into caverns for permanent waste disposal, or temporary energy storage (natural gas/compressed air/hydrogen) to alleviate the intermittency of wind/solar energy. We report here the results of the laboratory appraisal of the key properties of a thick Devonian rock salt formation in the Canning Basin (Western Australia). Two representative but contrasting lithofacies we...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...