The thermophilic methanogenic archaea Methanothermobacter spp. are applied as archaeal cell factories in industrial processes for methane production. Recently, secretion of commodity chemicals by M. marburgensis , such as amino acids, organic acids, or lipids has been observed. Together with the genetic tools available, genetically engineered cell factories for commodity chemical production from CO 2 can be developed. However,...

A multitude of anthropogenic stressors drive biodiversity loss and alter ecosystem functioning. Freshwaters, which contribute disproportionally to global biodiversity and biogeochemical cycles, are particularly threatened. Although the relationship between biodiversity and ecosystem functions (BEF) is generally well‐established, especially in terrestrial ecosystems, the role of multiple, co‐occurring stressors in modulating th...

Many species of river riparia are threatened by habitat loss due to altered flood and sediment regime, and associated shifts in vegetation structure. However, their ecological niche is often obscure, especially in inconspicuous organisms such as lichens, hindering their conservation and use as indicator species in river restoration. We studied if variation in sediment size distribution, gravel bank elevation and vegetation str...

Conservation planning that enhances the resiliency of biodiversity to climate change requires adaptive water and land use decision‐making in the most cost‐efficient way. This has many challenges since landscapes with high biodiversity can embrace intense human production activities, particularly agriculture. Conventionally, water and land used for conservation are often regarded as tradeoffs to agricultural productivity. Howev...

In Ireland, the Nahanagan Stadial (NS) was characterised by cirque glacier, plateau icefield and mountain ice cap expansion and is named after the cirque glacier type‐site of Lough Nahanagan in the Wicklow Mountains. This period is broadly equivalent to the Younger Dryas Stadial and Greenland Stadial‐1 (GS‐1: ~12.9–11.7 ka). Here, we provide the first evaluation of the full extent of NS glaciation in the Wicklow Mountains by c...

Rationale Glucagon-like peptide-1 (GLP-1) receptor agonists reduce alcohol consumption in rodents and non-human primates. Semaglutide is a new long-acting GLP-1 receptor agonist, widely used in the clinic against type 2 diabetes and obesity. It is also reported to reduce alcohol intake in rodents. Objectives This study investigates the possible inhibitory effect of semaglutide on alcohol intake in alcohol-preferring African gr...

Southern Africa has been strongly affected by ongoing climate change in recent decades. Rainfall variability is modulated by regional patterns of moisture advection and convergence in the lower troposphere. Using reanalysis, ground and satellite‐based rainfall products and observations from 10 weather stations, we perform a synoptic and climatological analysis focussing on atmospheric circulation, moisture transport and their...

Genetic susceptibility to familial colorectal cancer (CRC), including for individuals classified as Familial Colorectal Cancer Type X (FCCTX), remains poorly understood. We describe a multi-generation CRC-affected family segregating pathogenic variants in both BRCA1 , a gene associated with breast and ovarian cancer and RNF43 , a gene associated with Serrated Polyposis Syndrome (SPS). A single family out of 105 families meetin...

The CORDEX Flagship Pilot Study ELVIC (climate Extremes in the Lake VICtoria basin) was recently established to investigate how extreme weather events will evolve in this region of the world and to provide improved information for the climate impact community. Here we assess the added value of the convection-permitting scale simulations on the representation of moist convective systems over and around Lake Victoria. With this...

Aim Animal migration is often explained as the result of resource tracking in seasonally dynamic environments. Therefore, resource availability should influence both the distributions of migratory animals and their seasonal abundance. We examined the relationship between primary productivity and the spatio‐temporal distributions of migratory birds to assess the role of energy availability in avian migration. Location North Ame...

Insecure attachment, impaired personality structure and impaired emotion regulation figure prominently in substance use disorders. While negative emotions can trigger drug-use and relapse, cognitive reappraisal may reduce emotional strain by promoting changes in perspective. In the present study, we explored behavioral and neural correlates of cognitive reappraisal in poly-drug use disorder by testing individuals’ capability t...

To improve the understanding of gas transport processes in tight rocks (e.g., shales), systematic flow tests with different gases were conducted on artificial micro- to nanoporous analogue materials. Due to the rigidity of these systems, fluid-dynamic effects could be studied at elevated pressures without interference of poro-elastic effects. Flow tests with narrow capillaries did not reveal any viscosity anomaly in a confined...

A coherent synoptic sequence, mostly over North Africa, is identified whereby an upper‐level midlatitude trough (in November–March) excites several days of quasi‐stationary near‐surface warming across the Sahara, leading to rainfall events over northern Congo (NC), and perturbed weather more widely. Ahead of NC rainfall events, composite sequences first identify troughs for several days near Iberia, followed by relatively quic...

Ongoing loss of biological diversity is primarily the result of unsustainable human behavior. Thus, the long‐term success of biodiversity conservation depends on a thorough understanding of human–nature interactions. Such interactions are ubiquitous but vary greatly in time and space and are difficult to monitor efficiently at large spatial scales. However, the Information Age also provides new opportunities to better understa...