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North Pacific humpback whales are a celebrated conservation success, rebounding from extensive commercial whaling. Yet they remain vulnerable to the impacts of climate change, a multifaceted stressor that can exacerbate existing threats. During 2013–2016, a Northeast Pacific marine heatwave severely reduced forage availability in their feeding grounds, concurrent with diminished whale recruitment and increased mortality. We an...
Characterizing the genetic structure and connectivity between populations of endangered species can be used to inform management actions. In vagile species with high gene flow or recently established populations, such characterizations can be difficult to undertake using traditional genetic markers, and genetic stock identification (GSI) may be confounded by allele-sharing between populations. Loggerhead sea turtles ( Caretta...
Characterising the Radionuclide Fingerprint of an Advanced Gas-Cooled Nuclear Power ReactorNARA Subscribed
Radionuclides are monitored in the atmosphere for the signatures of nuclear explosions, as part of the verification of the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Civil nuclear facilities, such as Nuclear Power Plants (NPPs) and Isotope Production Facilities (IPFs) are sources of anthropogenic radionuclides in the atmosphere and these signatures are sometimes indistinguishable to those of a nuclear explosion. In order to...
Psilocybin therapy for treatment resistant depression: prediction of clinical outcome by natural language processingNARA Subscribed
Rationale Therapeutic administration of psychedelics has shown significant potential in historical accounts and recent clinical trials in the treatment of depression and other mood disorders. A recent randomized double-blind phase-IIb study demonstrated the safety and efficacy of COMP360, COMPASS Pathways’ proprietary synthetic formulation of psilocybin, in participants with treatment-resistant depression. Objective While the...
The importance of connectivity for freshwater organisms is widely recognised, yet in‐stream barriers associated with population declines and increased risk of extinction remain globally ubiquitous. Despite their negative consequences, these barriers can protect aquatic communities by limiting the spread of invasive species, leading to conflicting management goals in some regions. Selective fish passage is a solution for the co...
Year class strength is an important determinant of fish population size, but the drivers are often unknown. The northern stock of European sea bass ( Dicentrarchus labrax ) is an important target species for both commercial and recreational fisheries. Scientific assessments showed a rapid decline in spawning stock biomass from 2010-18 attributed to a combination of fishing mortality and poor year class strength. Recruitment to...
Evaluating changes to home bowel cancer screening kits: an end-user perspective studyNARA Subscribed
Purpose Many people do not participate in mail-out bowel cancer screening programs due to difficulties using the screening kit. The current study investigated the ways the screening kit could be modified to improve usability. Methods 1,109 people evaluated 15 different screening kit modifications. Participants reported on how these kit modifications would affect their screening barriers, their future screening intentions, and...
A Software Package for Radionuclide Detection Event AnalysisNARA Subscribed
The sea bass stock around the UK (northern stock) has declined rapidly over the past decade, likely due to a combination of both overfishing and low recruitment. Understanding mechanisms that drive the number of young reaching nursery grounds is important for explaining observed recruitment variability and therefore developing effective management strategies. An individual-based model (IBM) has been developed here to investiga...