This study aimed to evaluate the potential cost-effectiveness of implementing a prediction tool for estimating mild cognitive impairment (MCI) to dementia conversion risk. A decision-analytic model was developed to compare the costs and effects of current practice for subjects with MCI to a situation in which the risk of dementia is estimated using a prediction tool. Different scenarios in terms of prediction horizons, predict...

Armored urban shorelines have historically impoverished life on the waterfront. Materials and forms were chosen to discourage the settlement of marine communities and human access. This has weakened shoreline habitats and adjacent terrestrial and aquatic ecosystems and diminished urban human experiences by reducing links to nature. Augmentation of existing structures and new waterfront designs for specific ecological goals suc...

Vitamin D has a well‐established role in skeletal health and is increasingly linked to chronic disease and mortality in humans and companion animals. Despite the clear significance of vitamin D for health and obvious implications for fitness under natural conditions, no longitudinal study has tested whether the circulating concentration of vitamin D is under natural selection in the wild. Here, we show that concentrations of d...