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Streptomyces amazonensis sp. nov. isolated from Madeira river sediments with genomic potential for secondary metabolite productionNARA Subscribed
The genus Streptomyces is recognized as a source of secondary metabolites (SMs) with applications in medicine, industry, and agriculture. This study presents the description and characterization of a new Streptomyces species, isolated from sediments of the Madeira River in the Brazilian Amazon. Four strains (CPAA MAD 27, CPAA MAD 39, CPAA MAD 42, and CPAA MAD 51) were obtained from sampling sites distributed along the river. T...
Stable isotope analysis of green turtle ( Chelonia mydas ) scutes provides insights into long-term dietary patterns (~ 6.5 years). We analysed δ¹³C and δ¹⁵N values from nesting turtles in the Red Sea and combined these with macrophyte isotope data from the literature. Bayesian mixing models estimated dietary contributions by habitat and taxa. Seagrass meadows were the dominant inferred carbon source, contributing 90.1 ± 4.7%,...
Deep learning and geospatial approaches for post-flood disaster damage assessment: a systematic reviewNARA Subscribed
Extreme precipitation and flooding have demonstrated nature’s overwhelming force against human resilience, triggering geohazards such as landslides. These geohazards frequently cause infrastructure damage, resulting in power outages and loss of communications. This situation highlights the critical need for geospatial technologies to bridge data gaps in assessement of disaster-related damage. However, current literature typica...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
The genus Bacillus comprises Gram-positive, endospore-forming rods with a ubiquitous distribution across terrestrial, aquatic, and aerial environments, as well as associations with plants, animals, and food. To explore its diversity, we conducted an integrated phylogenomic and pangenome analysis using 10,839 publicly available RefSeq genomes (67 type strain genomes). Taxonomic delimitation combining genomic-distance metrics (M...
Cytotoxic edema (CE) is a radiographic marker of early tissue injury in cerebral venous thrombosis (CVT) associated with poor outcomes, yet its mechanistic pathway remains unclear. We investigated whether intraparenchymal hemorrhage (IPH) mediates the association between CE and outcomes. We conducted a retrospective cohort study using the multicenter CLOT-VENUS registry, including acute CVT patients treated at two Comprehensiv...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
The ecology of the Greater Caribbean manatee ( Trichechus manatus manatus ) remains underexplored in southern Central America, particularly in Panama and Costa Rica. This study presents, for the first time, significant information about their local and regional movements, connectivity, and residence times in various wetlands. Since 2016, we have employed acoustic monitoring to track the manatee population, identifying individu...