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Coastal waters are increasingly susceptible to low-oxygen conditions where circulation or nutrient inputs have been altered by anthropogenic activities, leading to increased occurrence of coastal hypoxia worldwide. Low-oxygen conditions also occur naturally in coastal settings, typically in bottom water or landward of sills where circulation is weak. Here we identify and characterize a persistent, low-oxygen layer in the mid-w...
Diet-dependent, beneficial and adverse effects of rapamycin on life span of Drosophila melanogasterNARA Subscribed
Rapamycin supplementation has been reported to extend life spans in numerous species, including Drosophila melanogaster , but a recent study in this laboratory revealed a marked life-shortening effect in y w male flies. The experiments reported here were performed to characterize conditions under which rapamycin could extend or shorten life spans in five fly strains. On a cornmeal/torula yeast-based medium, rapamycin extended...
Site Selection for Seaweed Biofilters Installation within the Great Barrier Reef World Heritage AreaNARA Subscribed
Elevated terrestrial nutrient loads entering coastal waters in northeastern Australia are adversely affecting the Great Barrier Reef World Heritage Area. ‘Seaweed biofilters’ have been proposed as a mechanism for the bioextraction of elevated nutrient levels from coastal environments, with potential to target diffuse source nutrient discharges while generating biomass with potential applications as fertiliser, soil conditionin...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Endemic species with narrow ranges are vulnerable to extirpation, and understanding their habitat needs is fundamental to effective management. The Etowah Bridled Darter, Percina freemanorum , is a recently described fish species endemic to the Upper Etowah River in Georgia. Little is known about how its habitat requirements differ from its sister taxon, P. kusha, with which it was previously synonymous . Our objectives were t...
HIV is highly comorbid with cocaine use disorder (CUD). Relapse is a major challenge in the treatment of CUD, and people living with HIV (PLWH) exhibit shorter time to relapse. One driver of relapse may be re-exposure to cocaine, which can be modeled in rodents using cocaine-primed reinstatement. This process involves neuroadaptations within the medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) shell, regions that me...
Why primatology needs local knowledgeNARA Subscribed
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Urbanization drives genetic erosion and population structure in a historically connected carnivore populationNARA Subscribed
Urbanization is a dominant driver of habitat fragmentation globally, creating small, isolated wildlife populations vulnerable to accelerated genetic drift, reduced genetic diversity, and increased population differentiation. We investigated how urban development affects the genetic structure of caracals ( Caracal caracal ) in Cape Town, South Africa using microsatellites and mitochondrial DNA sequence data. Sampling across fou...