Pathogenic variation of SLC26A 4 gene causes both Pendred syndrome (PDS) and non-syndromic enlarged vestibular aqueduct (NSEVA/DFNB4), two autosomal recessive disorders. The former accounts for approximately 6% of human genetic hearing loss, making it the second most common form of syndromic deafness after Usher syndrome, while the latter is the most common radiological malformation associated with childhood sensorineural hear...

Kelp forests are highly productive coastal ecosystems that sustain organic carbon cycling and diverse food webs; however, their ecosystem metabolism remains insufficiently quantified due to a lack of suitable in situ methods. In this study, the aquatic eddy covariance technique was used to quantify oxygen (O 2 ) flux and net ecosystem metabolism in Ecklonia cava forests along Jeju Island, Korea. We also applied partial least s...

Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...