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Baleen Whale Occurrence in the Waters Off Virginia and North Carolina, U.S.A. From 2001 to 2019NARA Subscribed
Eighteen years of visual survey and strandings data were used to describe baleen whale occurrence along the continental shelf of Virginia and North Carolina, U.S.A. This region experiences heavy anthropogenic use, which poses risks for mortality and injury to baleen whales. Between 2001 and 2019, six species of baleen whales were recorded, and whales occurred year‐round. The total number of (on‐ and off‐effort) sightings and s...
Genomic selection shows improved expected genetic gain over phenotypic selection of agronomic traits in allotetraploid white cloverNARA Subscribed
Key message Genomic selection using white clover multi-year-multi-site data showed predicted genetic gains through integrating among-half-sibling-family phenotypic selection and within-family genomic selection were up to 89% greater than half-sibling-family phenotypic selection alone. Abstract Genomic selection, an effective breeding tool used widely in plants and animals for improving low-heritability traits, has only recentl...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell deathNARA Subscribed
Aminoglycoside antibiotics are lifesaving medicines, crucial for the treatment of chronic or drug resistant infections. However, aminoglycosides are toxic to the sensory hair cells in the inner ear. As a result, aminoglycoside-treated individuals can develop permanent hearing loss and vestibular impairment. There is considerable evidence that reactive oxygen species (ROS) production and the subsequent phosphorylation of c-Jun...
Temporal stability vs. community matrix measures of stability and the role of weak interactionsNARA Subscribed
Relationships between different measures of stability are not well understood in part because empiricists and theoreticians tend to measure different aspects and most studies only explore a single form of stability. Using time‐series data from experimental plankton communities, we compared temporal stability typically measured by empiricists (coefficient of variation in biomass) to stability measures typically measured by theo...
p38 mitogen-activated protein kinases (P38α and β) and c-Jun N-terminal kinases (JNK1, 2, and 3) are key mediators of the cellular stress response. However, prolonged P38 and JNK signalling is associated with damaging inflammatory responses, reactive oxygen species–induced cell death, and fibrosis in multiple tissues, such as the kidney, liver, central nervous system, and cardiopulmonary systems. These responses are associated...
Phylogeography and bindin evolution in Arbacia , a sea urchin genus with an unusual distributionNARA Subscribed
Among shallow water sea urchin genera, Arbacia is the only genus that contains species found in both high and low latitudes. In order to determine the geographical origin of the genus and its history of speciation events, we constructed phylogenies based on cytochrome oxidase I and sperm bindin from all its species. Both the mitochondrial and the nuclear gene genealogies show that Arbacia originated in the temperate zone of th...
Infectious pancreatic necrosis (IPN) is a very serious viral disease in terms of its impact on production of Atlantic salmon, Salmo salar L., fry and post‐smolts. Post‐smolts of Atlantic salmon were injected with infectious pancreatic necrosis virus (IPNV) and cohabited with naive fish to produce natural infection. Cohabitant fish were sampled every 2 days, up to day 36 post‐infection (p.i.). From 90 cohabitant fish, 11 (12.2%...
Transcriptional and biochemical signatures of divergence in natural populations of two species of New Zealand alpine PachycladonNARA Subscribed
New Zealand is diverse in alpine and subalpine environments, a consequence of Late Tertiary tectonic and climatic change. However, few studies have sought to evaluate the importance of these environments as abiotic drivers in the diversification of plant species. Of particular interest is the Late Tertiary radiation of Pachycladon , an endemic New Zealand genus of alpine cress. Here we report observations on genome‐wide levels...