Understanding how genetic variants influence disease risk through molecular mechanisms remains a central challenge in complex disease genetics. Nonsyndromic orofacial clefts (OFCs) exemplify this challenge, with most risk loci residing in non-coding regions. We hypothesized that common genetic variants influence OFC risk by modulating DNA methylation at regulatory elements through methylation quantitative trait loci (meQTLs)....

The Eastern South Pacific (ESP) is a highly heterogeneous environment, characterized by a productivity gradient that goes from eutrophic waters in the coastal zone to ultraoligotrophic waters in the center of the South Pacific Gyre. Its coastal region is a significant source of CO 2 , CH 4 , and N 2 O to the atmosphere, mainly due to upwelled subsurface waters high in greenhouse gases (GHGs), where microbial processes produce...

The subfamily Aleocharinae (Coleoptera: Staphylinidae) comprises the most diverse lineage of beetles associated with eusocial insects, yet a large portion of its termitophilous diversity remains undocumented, particularly in the Neotropical region. Here, we describe Guaranguera zilbermani gen. et sp. n., a new termitophilous rove beetle discovered in nests of Cornitermes cumulans (Kollar, 1832) (Termitidae: Syntermitinae) in s...

Heavy metals and phenolic compounds are frequently present in industrial effluents. These accumulate in environmental matrices such as soil, air, and water due to their resistance to degradation, posing significant risks to ecosystems and human health. Here, sepiolite was grafted with (3-mercaptopropyl)trimethoxysilane, and MPTMS-Sep was used in the adsorption of Cu 2+ . Subsequently, Cu-MPTMS-Sep was evaluated in the photocat...