M. Petrillo results 4
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Retrieving sequences of genetically modified plants from public databases to widen screening approachesNARA Subscribed
The development of effective screening methods and implementation of official controls on genetically modified organisms (GMOs) relies heavily on the availability of comprehensive and reliable GMO sequence repositories. Existing GMO databases, including the one developed by the Joint Research Centre (JRC), do not cover all events authorised worldwide. To bridge this gap, we designed a bioinformatics pipeline to retrieve new GM...
The emergence of new SARS-CoV-2 variants poses challenges to global surveillance efforts, necessitating swift actions in their detection, evaluation, and management. Among the most recent variants, Omicron BA.2.86 and its sub-lineages have gained attention due to their potential immune evasion properties. This study describes the development of a digital PCR assay for the rapid detection of BA.2.86 and its descendant lineages,...
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesisNARA Subscribed
The Feline Leukemia Virus Subgroup C Receptor 1a (FLVCR1a) is a transmembrane heme exporter essential for embryonic vascular development. However, the exact role of FLVCR1a during blood vessel development remains largely undefined. Here, we show that FLVCR1a is highly expressed in angiogenic endothelial cells (ECs) compared to quiescent ECs. Consistently, ECs lacking FLVCR1a give rise to structurally and functionally abnormal...
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