The widespread use and production of plaster during the Neolithic transition in SW Asia represents a significant technological advancement and development in the material culture of early sedentary farming communities. The Final Pre-Pottery Neolithic case-study of Qdeir (7100 − 5720 cal BCE), located in the Syrian steppe, provides new evidence of resource management and technology in floor plaster manufacture. It also sheds li...

Regular, systematic, and independent assessments of computational tools that are used to predict the pathogenicity of missense variants are necessary to evaluate their clinical and research utility and guide future improvements. The Critical Assessment of Genome Interpretation (CAGI) conducts the ongoing Annotate-All-Missense (Missense Marathon) challenge, in which missense variant effect predictors (also called variant impact...