Earth's biodiversity is central to ecosystem health and resilience, providing essential functions and services. The Red Sea is a recognised marine biodiversity hotspot with high endemism and unique environmental conditions that support extensive but poorly resolved biodiversity. Here, we applied metagenomic analyses to sediment samples collected from coastal to deep‐sea environments during the Red Sea Decade Expedition 2022 to...

The purpose of the study is to evalute the in vivo anti -inflammatory activity of newly synthesized cyanoacetate derivatives of succinimides (C-23, C-31, and C-44) and to elucidate their possible mechanisms of action through key inflammatory mediator pathways. Anti-inflammatory activity was assessed using carrageenan-induced paw oedema and arachidonic acid-induced ear oedema models in vivo. Mechanistic involvement was investig...

Tanshinones, a class of lipophilic abietane-type diterpenoid, represents the major bioactive constituents of Salvia miltiorrhiza Bunge (Danshen), a key herb in traditional Chinese medicine with growing therapeutic importance. This review offers an in-depth overview of tanshinones from phytochemical and pharmacological perspectives. The review outlines the biosynthetic pathway, highlights the key synthetic approaches, and provi...