Purpose Many abdominal aortic aneurysm (AAA) patients develop intraluminal thrombus (ILT), but the role of ILT in AAA progression and rupture is poorly understood. Methods To evaluate ILT in AAAs, we induced AAAs in C57Bl6/J mice via surgical application of topical elastase to the abdominal aorta below the renal arteries and administration of β-aminopropionitrile (BAPN) in drinking water. Ultrasound images of these AAAs were c...

Rationale Attention-deficit hyperactivity disorder (ADHD) shows substantial heterogeneity in symptoms and cognitive deficits. According to the Triple Pathway Model, this variability may stem from impairments in three neuropsychological domains: inhibition, motivation, and temporal processing. Repeated low-dose administration of psychedelics is being explored as a treatment for ADHD, but evidence from controlled studies in this...

Late blight ( Phytophthora infestans ) and early blight ( Alternaria solani ) are the most important diseases in potato cultivation. The control of these diseases depends largely on fungicide sprays during the growing season. Fungicides differ in their efficacy to control any pathogen. The use of effective fungicides is necessary for both the control of the disease and to avoid unnecessary sprays. Each active ingredient has it...

Auditory speech is a highly relevant ecological stimulus with intrinsic temporal dynamics. At the cortical level, it is well established that neural responses contain information about the temporal dynamics of speech. Previous research further suggests that the basal ganglia also play a role in temporal processing. However, it is unknown whether neural responses in basal ganglia structures contain information about temporal sp...

Motivation Pollinators play a crucial role in maintaining Earth's terrestrial biodiversity. However, rapid human‐induced environmental changes are compromising the long‐term persistence of plant‐pollinator interactions. Unfortunately, we lack robust, generalisable data capturing how plant‐pollinator communities are structured across space and time. Here, we present the EuPPollNet (European Plant‐Pollinator Networks) database,...

To increase pollinator populations, international policy targets minimum levels of seminatural habitat cover, but it is unknown whether improving the quality of existing habitats could bring similar benefits without the need of reducing cropland area. Using data we collected in 26 Italian agricultural landscapes during the entire flying season, we explored the relative importance of habitat quantity (seminatural habitat cover)...

Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α‐diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e., γ‐diversity), either due to reduced β‐diversity amplifying diversity loss or increased β‐diversity dampening diversity loss. Additionally, studies often focus on taxo...

Seventy five percent of the world's food crops benefit from insect pollination. Hence, there has been increased interest in how global change drivers impact this critical ecosystem service. Because standardized data on crop pollination are rarely available, we are limited in our capacity to understand the variation in pollination benefits to crop yield, as well as to anticipate changes in this service, develop predictions, and...

Cartilage has little intrinsic capacity for repair, so transplantation of exogenous cartilage cells is considered a realistic option for cartilage regeneration. We explored whether human-induced pluripotent stem cells (hiPSCs) could represent such unlimited cell sources for neo-cartilage comparable to human primary articular chondrocytes (hPACs) or human bone marrow-derived mesenchymal stromal cells (hBMSCs). For this, chondro...

Scenario‐based biodiversity modelling is a powerful approach to evaluate how possible future socio‐economic developments may affect biodiversity. Here, we evaluated the changes in terrestrial biodiversity intactness, expressed by the mean species abundance (MSA) metric, resulting from three of the shared socio‐economic pathways (SSPs) combined with different levels of climate change (according to representative concentration p...

The sustainability of agriculture can be improved by integrating management of ecosystem services, such as insect pollination, into farming practices. However, large‐scale adoption of ecosystem services‐based practices in agriculture is lacking, possibly because growers undervalue the benefits of ecosystem services compared to those of conventional management practices. Here we show that, under representative real‐world condit...

Mass‐flowering crops ( MFC s) are increasingly cultivated and might influence pollinator communities in MFC fields and nearby semi‐natural habitats ( SNH s). Across six European regions and 2 years, we assessed how landscape‐scale cover of MFC s affected pollinator densities in 408 MFC fields and adjacent SNH s. In MFC fields, densities of bumblebees, solitary bees, managed honeybees and hoverflies were negatively related to t...