Alzheimer’s disease (AD) affects more than 55 million people worldwide, yet current theories cannot fully explain its aetiology. Accordingly, gene expression profiling has been used to provide a holistic view of the biology underpinning AD. Focusing primarily on protein-coding genes, such approaches have highlighted a critical involvement of microglia-related inflammatory processes. Simultaneous investigation of transcriptiona...

Genomic data from historical specimens can provide insights into populations and processes no longer evident from modern samples. Identifying viable sources of historical DNA is key to this. Here we aimed to explore the viability of trophy hunting paws as sources of historical DNA, and to use this data for preliminary analyses to evaluate changes in population structuring over time. We aimed to search for the presence of genom...

Threats to coastal wetlands, including sea-level rise and subsidence, led the National Wildlife Refuge (NWR) System to protect over 500,000 hectares of coastal wetlands during the twentieth century, with approximately 20% occurring in the South Atlantic geography. This effort has involved systematic long-term monitoring of changes in marsh elevation using surface elevation tables and marker horizons at 20 sites across 19 NWRs...

Marine community science presents an important route to gather valuable scientific information while also influencing local management and policy, thus contributing to marine conservation efforts. Because seahorses are cryptic but charismatic species, they are good candidates for engaging diverse people to help overcome the many gaps in biological knowledge. We have synthesized information contributed to the community science...

We set out to reveal the effects of long-term changes in land use and long-term average climate on the regional biophysical environment in southern Malawi. Object-oriented supervised image classification was performed on Landsat 5 and 8 satellite images from 1990 to 2020 to identify and quantify past and present land use-land cover changes using a support vector machine classifier. Subsequently, using 2000 and 2010 land use-la...

The gut microbiota have important consequences for host biological processes and there is some evidence that they also affect fitness. However, the complex, interactive nature of ecological factors that influence the gut microbiota has scarcely been investigated in natural populations. We sampled the gut microbiota of wild great tits ( Parus major ) at different life stages allowing us to evaluate how microbiota varied with re...

Carbon‐concentrating mechanisms (CCMs) are a widespread phenomenon in photosynthetic organisms. In vascular plants, the evolution of CCMs ([C44‐carbon compound] and crassulacean acid metabolism [CAM]) is associated with significant shifts, most often to hot, dry and bright, or aquatic environments. If and how CCMs drive distributions of other terrestrial photosynthetic organisms, remains little studied. Lichens are ecologicall...