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Border protected areas (BPAs) are national protected areas that are immediately adjacent to a country's border or span two or more countries; they are characterized by distinctive opportunities and pressures. They play a critical role in protecting carbon‐rich ecosystems, conserving endangered biodiversity, reducing cross‐border environmental threats, and promoting peace and cooperation. At the same time, compared with other p...
A primary care pharmacogenetic precision medicine pilot based on specific Māori tribal ethical frameworks and principlesNARA Subscribed
Indigenous tribal communities are frequently underserved by genomic medicine because they are under-represented in research, often live in remote locations and have ethical and cultural perspectives that vary from westernised standpoints. The Rakeiora platform, a permissioning and analytical environment that incorporates Māori perspectives and ethical frameworks on how precision medicine research is best conducted was used to...
Maritime Domain Awareness increasingly depends on publicly available vessel tracking data to support commercial fisheries oversight, but it remains unclear how closely publicly available AIS-derived products approximate the restricted Vessel Monitoring System data that have long served as the regulatory standard. Here we evaluate whether two no-cost public AIS-derived platforms can substitute for restricted VMS data in the eas...
Fine‐Scale Ecological Biomonitoring in a Large, Complex Agriculturally Impacted Watershed via eDNA MetabarcodingNARA Subscribed
DNA‐based approaches utilizing high‐throughput sequencing (HTS) (e.g., DNA metabarcoding) have revolutionized ecological biomonitoring by providing higher sample throughput, greater reproducibility, and better cost‐benefits compared to traditional morphology‐based bioassessment studies. Here, we utilized DNA metabarcoding in a watershed in Ontario (Canada) dominated by agricultural land uses. Our aim is to understand patterns...
Introduction Toxicologists may use high dose n-acetylcysteine (HD-NAC) for early-treated high-risk acetaminophen ingestions (EHRAI) given concerns over standard NAC (S-NAC) dosing’s efficacy. We utilize the novel, clinically relevant outcome of mean additional 16-hour NAC maintenance infusions (NMI) to evaluate differences in treatment duration for EHRAI patients treated with S-NAC versus HD-NAC. Methods Retrospective multista...
In many settings, head and neck cancer (HNC) services are centralized in large hospitals, meaning that community input from HNC specialists can be lacking. Community healthcare professionals often require laryngectomy-specific education and training to provide optimal care to people at home. However, laryngectomy-specific education/training is often sporadic and varies between centres, making it difficult to achieve standardis...