M. Wunderlich results 13
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Primate populations worldwide are experiencing rapid declines due to habitat loss, degradation, and overexploitation. These pressures are particularly severe across sub-Saharan Africa and the Gulf of Guinea biodiversity hotspot, which supports several threatened and endemic species. The Ebo-Makombe-Ndokbou forests in southwestern Cameroon contain critical habitat for several of these species, including the Critically Endangere...
Machine Learning–Based Identification of Target Groups for Thrombectomy in Acute StrokeNARA Subscribed
Whether endovascular thrombectomy (EVT) improves functional outcome in patients with large-vessel occlusion (LVO) stroke that do not comply with inclusion criteria of randomized controlled trials (RCTs) but that are considered for EVT in clinical practice is uncertain. We aimed to systematically identify patients with LVO stroke underrepresented in RCTs who might benefit from EVT. Following the premises that (i) patients witho...
The effect of BI 409306 on heart rate in healthy volunteers: a randomised, double-blind, placebo-controlled, crossover studyNARA Subscribed
Purpose The potent, selective phosphodiesterase-9A inhibitor BI 409306 may be beneficial for patients with attenuated psychosis syndrome and could prevent relapse in patients with schizophrenia. Transient BI 409306-dependent increases in heart rate (HR) demonstrated previously necessitated cardiac safety characterisation. We evaluated cardiac effects of BI 409306 in healthy volunteers during rest and exercise. Methods In this...
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