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Thermokarst lake and drained lake basin (DLB) dynamics are intensifying across the Alaskan Arctic Coastal Plain. Thawing, drainage, and erosion expose surface and deep sediments (> 1 m) to aerobic conditions, with saline deposits being particularly vulnerable due to freeze‐point depression. As organic carbon mineralization remains poorly constrained, we determined potentials with an aerobic one‐year long incubation at 10°C in...
2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinasesNARA Subscribed
Angiogenesis is a crucial process in the progression of various pathologies, like solid tumors, wet age-related macular degeneration, and chronic inflammation. Current anti-angiogenic treatments still have major drawbacks like limited efficacy in diseases that also rely on inflammation. Therefore, new anti-angiogenic approaches are sorely needed, and simultaneous inhibition of angiogenesis and inflammation is desirable. Here,...
Groundwater flow below construction pits and erosion of temporary horizontal layers of silicate groutingNARA Subscribed
Injection of silicate grouting materials is widely used to create temporary horizontal layers for reducing inflow of groundwater at construction sites, in regions with shallow water tables. The erosion of a grouting layer was investigated by means of analytical solutions for groundwater flow and transport within a pit after construction finished. Erosion is assumed to occur by dissolution of the temporary injection layer and s...
Previous paleolimnological studies demonstrated that the sediments of Garba Guracha, situated at 3950 m asl in the afro-alpine zone of the Bale Mountains of Ethiopia, provide a complete Late Glacial and Holocene paleoclimate and environmental archive. We revisited Garba Guracha in order to retrieve new sediment cores and to apply new environmental proxies, e.g. charcoal, diatoms, biomarkers, and stable isotopes. Our chronology...
Land-use effects on phosphorus fractions in Cerrado oxisolsNARA Subscribed
Neurotoxic esteraseNARA Subscribed
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