M.R. Nelson results 235
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Timing of water limitation moderates drought hardiness traits of western larch (Larix occidentalis) seedlingsNARA Subscribed
Water limitation during tree seedling cultivation can promote traits that improve drought hardiness. Nurseries apply water limitation mostly during a brief developmental window of seedling growth, which may restrict the range of useful traits achievable through water limitation if phenotypic responses differ across ontogeny. We characterized the diversity of western larch ( Larix occidentalis (Nutt.)) seedling traits produced...
Rationale Affective behavioral effects of kappa-opioid receptor (KOR) stimulation have been found to vary between the rostral and caudal nucleus accumbens (NAc) shell, but this has so far only been demonstrated in males. Objectives To examine the effects of KOR activation in subregions of the NAc shell on affective and motivated behavior in females. Methods In one group of Long-Evans rats, females were given access to 20% etha...
A Coast-to-Coast Assessment of Cumulative Impacts and Protection Potential in Canadian Marine Conservation NetworksNARA Subscribed
The effectiveness of marine conservation networks depends on their ability to manage and safeguard against the many overlapping human activities and stressors influencing marine ecosystems. Cumulative impact mapping (CIM) combines information on the intensity and location of stressors with the spatial extent and vulnerability of marine habitats to generate a single, relative cumulative impact (CI) score. Despite its potential...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Pedicularis furbishiae is a globally rare, hemiparasitic perennial restricted to dynamic riverbank habitats along the Wolastoq (Saint John) River in Maine, USA, and New Brunswick, Canada. The species now faces severe threats from habitat fragmentation, altered hydrology, and demographic collapse—particularly in New Brunswick, where several subpopulations have been recently extirpated and where recovery activities are being und...
Terrigenous inputs link nutrient dynamics to microbial communities in a tropical lagoonNARA Subscribed
Nutrient availability drives community structure and ecosystem processes, especially in tropical lagoons that are typically oligotrophic but often receive allochthonous inputs from land. Terrestrially derived nutrients are introduced to tropical lagoons by surface runoff and submarine groundwater discharge, which are influenced by seasonal precipitation. However, terrigenous inputs presumably diminish along the onshore–offshor...
The key mechanisms associated with the survival of Gulf toadfish, Opsanus beta , when in severe hypoxiaNARA Subscribed
Florida's shallow seagrass beds experience daily diurnal fluctuations in environmental oxygen, leading to hypoxic episodes (PO 2 −1 , ~6 kPa) that have increased in frequency and intensity in recent decades. The native Gulf toadfish ( Opsanus beta ) have been shown to employ a suite of adaptive cardiovascular, ventilatory and metabolic adjustments to survive moderate hypoxia, but little is known of the mechanisms used to survi...