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Ontogeny of drug-induced fatty liver disease (DIFLD): from key initiating events to disease phenotypesNARA Subscribed
We conducted an expert review of clinical case reports on drug-induced fatty liver disease (DIFLD) to classify drugs according to distinct clinical phenotypes. Seven clusters were identified based on clinical, biochemical, and histological features reflecting drug toxic mechanisms: Cluster 0 (Control): Drugs with no known steatotic effects or clinical evidence of DIFLD. Cluster 1: Drugs with mild pro-steatotic effects, exacerb...
Sea turtles are highly migratory species that can travel vast distances between their feeding and breeding sites. Considering the vulnerability and conservation concern of most sea turtle species, it is essential to establish connections between foraging and nesting areas to link threats at seas with the affected populations. Previous studies analyzed the population of origin for loggerhead turtles (Caretta caretta) in most kn...
BrainAGE in superagers: cross-sectional and longitudinal analyses in older adults aged 80+ with youthful episodic memoryNARA Subscribed
Episodic memory, the ability to recall past events, is particularly vulnerable to ageing. A decline in episodic memory performance is generally considered part of ageing. However, the episodic memory performance of superagers —defined as individuals aged 80+ years old with episodic memory of people 30 years younger— is superior to that typical of their chronological age. The aim of this study was to determine whether the discr...
Cortical volumetry and longitudinal cognitive changes in Parkinson’s disease: insights from the COPPADIS cohortNARA Subscribed
Cognitive decline is a major non-motor symptom in Parkinson’s disease (PD), often linked to brain atrophy. This study examines the relationship between cortical atrophy and age groups in predicting cognitive decline in PD over five years. 188 PD patients from the COPPADIS cohort were stratified by age: young (30–55 years, N = 47), middle-aged (56–65 years, N = 59), and older adults (66–75 years, N = 82). Baseline cortical volu...
In response to global climate change, numerous taxa are expanding their living ranges. In highly migratory species such as sea turtles, this expansion may be driven by individuals from nearby or distant areas. Recent nests outside the species' typical nesting range and reports of adult‐sized individuals in the western Mediterranean suggest a green turtle ( Chelonia mydas ) range expansion into the central and western Mediterra...
A relational turn in climate change adaptation: Evidence from urban nature-based solutionsNARA Subscribed
The emergence of nature-based solutions (NbS) in science, policy, and practice signals a paradigmatic shift in urban climate change adaptation, yet empirical investigations into its impact on adaptation definitions and progress tracking remain scarce. Addressing this gap, we conducted thematic analysis on semi-structured interviews ( n = 15) with practitioners responsible for implementing and evaluating urban NbS in different...
Polyurethane foam degradation combining ozonization and mealworm biodegradation and its exploitationNARA Subscribed
The biodegradation of polyurethane foam (PU foam) using a combination of oxidative pre-treatment (ozonization) and Tenebrio molitor ( T. molitor ) mealworms was conducted in this study. Different degrees of ozone oxidation (0%, 25%, and 50%) were applied to PU foam, which was subsequently fed to mealworms. The mealworms’ survival and growth were then compared to mealworms receiving a normal diet (bran). Results showed that mea...
The past, the recent, and the ongoing evolutionary processes of the worldwide invasive ascidian Styela plicataNARA Subscribed
Invasive species are one of the main threats to global biodiversity and, within marine ecosystems, tunicates feature some prominent examples. Styela plicata is an ascidian species inhabiting harbours in all temperate oceans and seas, thus being considered a thriving invasive species. However, this species' adaptive mechanisms, introduction history, and population structure have never been completely elucidated. Here, by genoty...