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Dermatophyte infections have evolved in both clinical presentation and etiological profiles, with chronic, recurrent, and widespread forms becoming increasingly prevalent and therapeutically challenging over the past decade. These infections are predominantly caused by Trichophyton indotineae (ITS genotype VIII), a member of the Trichophyton mentagrophytes complex. The virulence mechanisms of T . indotineae remain poorly under...
Clinical and Mycological Profiles of Chronic and Recalcitrant Dermatophytosis: Türkiye, 2022–2024NARA Subscribed
This study investigated the treatment outcomes of 91 patients with chronic and recalcitrant dermatophytosis from 20 hospitals in Türkiye between June 2022 and March 2024, as well as the in vitro antifungal susceptibility and squalene epoxidase ( SQLE ) substitution profiles of the dermatophytes obtained from these patients. Molecular identification by sequencing 91 isolates, revealed 76 Trichophyton mentagrophytes ITS genotype...
qPCR-Based Molecular Detection of Trichophyton indotineae by Targeting Divergent SequencesNARA Subscribed
Trichophyton indotineae , formerly known as T . mentagrophytes internal transcribed spacer (ITS) genotype VIII, has been recognized over the last decade due to its high virulence and resistance to treatment. Its accurate identification in routine mycology laboratories remains challenging, as it shares phenotypic traits and substantial rDNA ITS similarity with T . mentagrophytes and T . interdigitale . This study aimed to ident...
200 years of taxonomic confusion: Sporendonema and alliesNARA Subscribed
The genus Sporendonema ( Gymnoascaceae , Onygenales ) was introduced in 1827 with the type species S . casei for a red mould on cheese. Cheese is a consistent niche for this species. Sphaerosporium equinum is another species classified in Gymnoascaceae and has also been reported from cheese. Recently, other habitats have been reported for both Sporendonema casei and Sphaerosporium equinum . The present study aimed to investiga...
Fundamental niche prediction of the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii in EuropeNARA Subscribed
Summary Fundamental niche prediction of Cryptococcus neoformans and Cryptococcus gattii in Europe is an important tool to understand where these pathogenic yeasts have a high probability to survive in the environment and therefore to identify the areas with high risk of infection. In this study, occurrence data for C . neoformans and C . gattii were compared by MaxEnt software with several bioclimatic conditions as well as wit...