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Naunyn-Schmiedeberg's Archives of Pharmacology · 2026 · Vol. 399 · Issue 1 · Springer
Spontaneous intracerebral hemorrhage (sICH) is a serious form of stroke associated with high mortality and poor functional outcomes. Hematoma expansion critically affects prognosis, necessitating early intervention. Tranexamic acid (TXA), an antifibrinolytic, has an uncertain role in sICH. This meta-analysis synthesizes evidence from randomized controlled trials (RCTs) to evaluate the efficacy and safety of TXA in sICH. Compre...