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NARA Subscribed2
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Springer Nature2
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Pharmaceutical Research2
Publication Year
20241
20201
Manting Chiang results 2 · Newest (Page 1/1, per page 25)
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Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous SystemNARA Subscribed
Pharmaceutical Research · 2024 · Vol. 41 · Issue 7 · Springer
Manting Chiang; Hyunmoon Back; Jong Bong Lee; Sarah Oh; Tiffany Guo; Simone Girgis; Celine Park; Simon Haroutounian; Leonid Kagan
Purpose Serotonin (5-HT 3 ) receptor antagonists are promising agents for treatment of neuropathic pain. However, insufficient drug exposure at the central nervous system (CNS) might result in lack of efficacy. The goal of this study was to evaluate the impact of administration of a Pgp inhibitor (tariquidar) on ondansetron exposure in the brain, spinal cord, and cerebrospinal fluid in a wild-type rat model. Methods Ondansetro...
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Pharmacokinetic Modeling of the Impact of P-glycoprotein on Ondansetron Disposition in the Central Nervous SystemNARA Subscribed
Pharmaceutical Research · 2020 · Vol. 37 · Issue 10 · Springer
Manting Chiang; Hyun-moon Back; Jong Bong Lee; Sarah Oh; Tiffany Guo; Simone Girgis; Celine Park; Simon Haroutounian; Leonid Kagan
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