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The novelty of this study lies in the integration of fermentation in a magnetically stabilized fluidized bed bioreactor with S. cerevisiae supported on calcium alginate with magnetic particles and using levoglucosan, a pyrolytic sugar from sugarcane bagasse, as a substrate for bioethanol production. Sugarcane bagasse was pretreated with acetic acid to remove alkali/alkaline earth metals (AAEMs) aiming to intensify levoglucosan...
Defining an ageing-related pathology, disease or syndrome: International Consensus StatementNARA Subscribed
Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased health span. With advancing age, the increased prevalence of ageing-related diseases can have a significant impact on health status, functional capacity and quality of life. It is therefore vital to develop comprehensive classification and staging systems for ageing-related pathologies, diseases and syndrom...
Alternative tissue fixation for combined histopathological and molecular analysis in a clinically representative settingNARA Subscribed
Formalin is the principal tissue fixative used worldwide for clinical and research purposes. Despite optimal preservation of morphology, its preservation of DNA and RNA is poor. As clinical diagnostics increasingly incorporates molecular-based analysis, the requirement for maintaining nucleic acid quality is of increasing importance. Here we assess an alternative non-formalin-based tissue fixation method, PAXgene Tissue system...
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