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Environmental vibrio phage–bacteria interaction networks reflect the genetic structure of host populationsNARA Subscribed
Phages depend on their bacterial hosts to replicate. The habitat, density and genetic diversity of host populations are therefore key factors in phage ecology, but our ability to explore their biology depends on the isolation of a diverse and representative collection of phages from different sources. Here, we compared two populations of marine bacterial hosts and their phages collected during a time series sampling program in...
The alternative sigma factor σ B plays a crucial role in adaptive strategies of Clostridium difficile during gut infectionNARA Subscribed
Summary Clostridium difficile is a major cause of diarrhoea associated with antibiotherapy. Exposed to stresses in the gut, C. difficile can survive by inducing protection, detoxification and repair systems. In several firmicutes, most of these systems are controlled by the general stress response involving σ B . In this work, we studied the role of σ B in the physiopathology of C. difficile . We showed that the survival of th...
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