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Providing regular and frequent maps of losses and gains of farmland birds based on European monitoring dataNARA Subscribed
Knowledge of species distributions is essential for informing policies on nature conservation and restoration. However, updating them on a regular basis and doing so in a harmonized manner at the international level is difficult. The European Bird Census Council integrated national monitoring data covering 5 years to update farmland bird distributions and assessed how they changed. We used these data on 50 farmland bird specie...
Raising awareness on algal toxins—a discussion on potential pathways of microcystins to urban groundwater systemsNARA Subscribed
Accelerated by urbanization, as well as by agricultural intensification and climate change, increasing nutrient fluxes towards surface waters and increasing water temperatures are increasing the probability for cyanobacterial harmful algal blooms. Significant deterioration of water quality occurs with such events when microcystins (MCs) are released as the most prominent algal toxins. Despite the typical assumption that MCs ar...
Urban boundary layer (UBL) processes are important to understand the complex interactions between the surface and atmosphere. Increased surface roughness and heat storage are typically attributed to the larger fraction of built surfaces in urban areas. Heatwaves lead to stronger heat storage and to extreme convective UBLs, which is one of many applications where large-eddy simulations (LES) offer an accurate modelling methodol...
Bridging the Energy Balance Gap in Eddy‐Covariance Measurements: Insights From Standardized Network DataNARA Subscribed
The lack of energy balance closure in Eddy‐Covariance (EC) measurements is a well‐known, still unresolved challenge in micrometeorology, with energy balance closure (EBC) rates typically ranging between 60% and 80%. While numerous hypotheses have been proposed to explain this imbalance, the relative contributions of neglected energy storage terms, data quality and flux processing options remain insufficiently disentangled. Usi...
Small Molecules to Elevate Rab7-GTPase Activity and Lower Cholesterol Accumulation in Niemann-Pick Type C DiseaseNARA Subscribed
Purpose Niemann-Pick type C (NPC) disease caused by mutations in cholesterol transporters NPC1 or NPC2 is characterized by cholesterol accumulation in late endosomes/lysosomes (LE/Lys). The activation of alternative cholesterol export routes that can bypass NPC1/2 deficiency could provide therapeutic opportunities. We previously demonstrated that gene depletion of the Rab7-GTPase activating protein (GAP) TBC1D15, which hydroly...