The host’s ability to clear parasites (resistance) and their capacity to reduce the impact of a given parasite burden (tolerance) is often described under conditions of a single pathogen challenge. We developed a mouse infection model to investigate the impact of co-infection on host resistance and tolerance to Heligmosomoides bakeri . C57BL/6 mice were infected with the helminth parasite H. bakeri and Theiler’s murine encepha...