Purpose We conducted a comprehensive analysis of esketamine-related adverse events (AE) on the FDA Adverse Event Reporting System (FAERS) database, taking into account for the first time drug-drug interaction signals. Methods We conducted a retrospective case/non-case study of esketamine-related AEs reported in the FAERS database up to the last quarter (Q4) of 2024. Potential signals were detected using the reporting odds rati...

We conducted paired measurements of the Sr/Ca ratio and oxygen and carbon stable isotopes of a fossil Faviidae coral specimen (MYK90), age 16 ka, collected from near Miyako Island, the Ryukyus, southwestern Japan. Our study aimed to reconstruct the palaeoenvironment in the East China Sea at 16 ka by comparing the fossil sample with modern Faviidae corals. Our data with annual or longer time resolution may be very suitable for...