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Genome-wide exploration of biosynthetic gene clusters and their association with virulence in the entomopathogenic fungus BeauveriaNARA Subscribed
Species of the genus Beauveria are widely used as biological control agents due to their ability to infect and kill a broad range of arthropod pests. Despite their agricultural importance, the genomic diversity underlying virulence and secondary metabolism across the genus remains uncharacterized. In this study, we performed a comprehensive phylogenomic and biosynthetic gene cluster (BGC) analysis of 322 high-quality Beauveria...
Associations of host gene expression in the brain, liver, muscle with fecal and cecal microbiota composition in pigsNARA Subscribed
Understanding the genetic regulation underlying host–microbiota interactions is key to elucidating how microbial communities influence host metabolism, immunity, and physiology. In this context, the main objective of this study was to integrate genomic, transcriptomic, and microbial data to identify shared regulatory variants, highlight key microbial taxa, and prioritize biological pathways related to lipid metabolism, immune...
Whole blood transcriptome signature predicts severe forms of COVID-19: Results from the COVIDeF cohort studyNARA Subscribed
COVID-19 is associated with heterogeneous outcome. Early identification of a severe progression of the disease is essential to properly manage the patients and improve their outcome. Biomarkers reflecting an increased inflammatory response, as well as individual features including advanced age, male gender, and pre-existing comorbidities, are risk factors of severe COVID-19. Yet, these features show limited accuracy for outcom...