Purpose To report a case of avian dermatitis associated with Microlichus sp. (Acari: Epidermoptidae) in a free-ranging Pitangus sulphuratus (Great Kiskadee) from southern Brazil, emphasizing the clinical presentation and parasitological diagnosis. Methods A juvenile P. sulphuratus was rescued and admitted to a wildlife rehabilitation center presenting feather loss and cutaneous lesions. Crust samples were collected from affect...

Dilated cardiomyopathy (DCM) is the third most common cause of heart failure. The multidisciplinary nature of testing — involving genetics, imaging, or cardiovascular techniques — makes its diagnosis challenging. Novel and reliable biomarkers are needed for early identification and tailored personalized management. Peripheral circular RNAs (circRNAs), a leading research topic, remain mostly unexplored in DCM. We aimed to asses...

Astrocyte activation is characterized by hypertrophy with increased glial fibrillary acidic protein (GFAP), whose expression may involve pro-inflammatory cytokines. In this study, the effects of pro-inflammatory IL-6 and TNF-α and anti-inflammatory cytokines IL-4 and IL-10 on nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signalling, intracellular calcium concentration ([Ca 2+ ] i ) and GFAP expression were investigat...

The natriuretic peptide (NP) system comprises of three ligands, the Atrial Natriuretic Peptide (ANP), Brain Natriuretic peptide (BNP) and C-type Natriuretic peptide (CNP), and three natriuretic peptide receptors, NPRA, NPRB and NPRC. Here we present a comprehensive study of the natriuretic peptide system in healthy murine and human submandibular salivary glands (SMGs). We show CNP is the dominant NP in mouse and human SMG and...

This paper analyzes the differences between ERA-Interim and ERA5 surface winds fields relative to Advanced Scatterometer (ASCAT) ocean vector wind observations, after adjustment for the effects of atmospheric stability and density, using stress-equivalent winds (U10S) and air–sea relative motion using ocean current velocities. In terms of instantaneous root mean square (rms) wind speed agreement, ERA5 winds show a 20 % improve...