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Springer Nature1
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BioMetals1
Publication Year
20261
Maria G. Ledesma-Colunga results 1 · Newest (Page 1/1, per page 25)
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Author: Maria G. Ledesma-Colunga ×Clear All Filters
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Iron overload induced by ferric derisomaltose and ferric carboxymaltose both increase FGF-23 levels and lead to osteomalacia and bone loss in normal miceNARA Subscribed
BioMetals · 2026 · Vol. 39 · Issue 3 · Springer
Xuan-Thanh Le-Phuoc; Vanessa Passin; Maria G. Ledesma-Colunga; Heike Weidner; Imke Fiedler; Björn Busse; Ulrike Baschant; Lorenz C. Hofbauer; Martina Rauner
Ferric carboxymaltose (FCM) and ferric derisomaltose (FDI) are key for treating iron deficiency anemia. However, FCM has been shown to raise serum fibroblast growth factor (FGF)-23 levels, causing hypophosphatemia and alterations in bone turnover in some patients. To date, it is unknown if FCM and FDI also affect bone mineralization. This study examined FDI and FCM effects on bone mineralization and FGF-23 in healthy mice, avo...
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