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Biotransformation of ketamine in terminal in vivo experiments under chronic intermittent hypoxia conditions and the role of AhRNARA Subscribed
We were pioneers in describing aryl hydrocarbon receptor (AhR) activation by chronic intermittent hypoxia (CIH) in a rat pre-clinical model. This model mimics hypertension (HTN) secondary to obstructive sleep apnea, enabling longitudinal investigation of hypertension development. Concerns about the influence of barbiturates on AhR-regulated enzymes led us to opt for ketamine/medetomidine anesthesia in terminal in vivo experime...
Song Notes and Patterns of the Mediterranean Fin Whale (Balaenoptera physalus) in the Ionian SeaOA Marine
The Mediterranean fin whale emits two types of 20-Hz calls, known as “classic” and “backbeat”, that can be produced in irregular series or in patterned sequences called songs. The analysis of songs is recognized as a meaningful approach to study baleen whales and can be used to investigate populations’ identities. Mediterranean fin whale songs have been studied previously, but only in the western Mediterranean Sea. This work d...
Exposure to environmental pollutants and attention-deficit/hyperactivity disorder: an overview of systematic reviews and meta-analysesNARA Subscribed
Although heritability estimates suggest a role for genetic components, environmental risk factors have been described as relevant in the etiology of attention deficit/hyperactivity disorder (ADHD). Several studies have investigated the role of toxicological pollution, i.e., air pollution, heavy metals, POPs, and phthalates. Clear evidence for association of ADHD and environmental factors has not been provided yet. To answer th...
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