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Springer Nature1
Journal
Molecular Neurobiology1
Publication Year
20211
Maria Nicol Colombo results 1 · Newest (Page 1/1, per page 25)
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Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in MiceNARA Subscribed
Molecular Neurobiology · 2021 · Vol. 58 · Issue 12 · Springer
Anna Longatti; Luisa Ponzoni; Edoardo Moretto; Giorgia Giansante; Norma Lattuada; Maria Nicol Colombo; Maura Francolini; Mariaelvina Sala; Luca Murru; Maria Passafaro
Rho GTPases are a class of G-proteins involved in several aspects of cellular biology, including the regulation of actin cytoskeleton. The most studied members of this family are RHOA and RAC1 that act in concert to regulate actin dynamics. Recently, Rho GTPases gained much attention as synaptic regulators in the mammalian central nervous system (CNS). In this context, ARHGAP22 protein has been previously shown to specifically...
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