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Biomedical Large Language Models and Prompt Engineering for Causality Assessment of Individual Case Safety Reports in PharmacovigilanceNARA Subscribed
Background Biomedical Large Language Models (LLMs) combined with prompt engineering offer domain-specific reasoning, yet their application to individual-level causality assessment remains unexplored. This study evaluated five combinations of biomedical LLMs, prompting strategies, and causality algorithms by comparing their agreement with two human expert evaluators. Research Design and Methods. A total of 150 Individual Case S...
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