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Beyond the BRCA1/2 genes in ovarian cancer: the role of germline pathogenic variants in the ATM geneNARA Subscribed
Background Ovarian Cancer (OC) prevention and early-stage detection represents a challenge due to the lack of effective surveillance. The identification of high-risk women is crucial as it provides access to prophylactic oophorectomy and reduces disease burden. Next-Generation Sequencing approaches enable the investigation of several genes associated with monogenic hereditary cancer predisposition, including ovarian cancer. Fo...
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