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Stability studies with tigecycline in bacterial growth medium and impact of stabilizing agentsNARA Subscribed
Purpose This study aimed to examine the degradation of tigecycline in Mueller Hinton broth (ca-MHB), as knowledge about bacterial susceptibility is key for therapeutic decisions. Methods Antioxidative stabilizers were evaluated on tigecycline stability in a quantitative chromatography assay and tigecycline induced kill against Staphylococcus aureus (ATCC29213) was determined in time kill studies. Results Ascorbic acid caused r...
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