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European Journal of Clinical Microbiology & Infectious Diseases · 2021 · Vol. 40 · Issue 1 · Springer
Purpose This study aimed to examine the degradation of tigecycline in Mueller Hinton broth (ca-MHB), as knowledge about bacterial susceptibility is key for therapeutic decisions. Methods Antioxidative stabilizers were evaluated on tigecycline stability in a quantitative chromatography assay and tigecycline induced kill against Staphylococcus aureus (ATCC29213) was determined in time kill studies. Results Ascorbic acid caused r...